Sweden Job Openings

AstraZeneca

Postdoctoral Fellow – Development of advanced genome editing methods

Gothenburg

FULL TIME

September 20, 2024

Are you ready to revolutionize biology research and genetic disease treatment? Are you driven by your desire to understand and reveal new insights? If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be.

Gene Editing by CRISPR-Cas9 has revolutionized biology research and genetic disease treatment. At Astra Zeneca and Promega, we are developing state-of-the-art genome editing tools applied to drug discovery. We are now joining forces to further develop our recent described PEn technology and apply the learning from this collaboration to model development and disease treatment. Do you want to be part of this unique effort?

About the opportunity
We are currently looking for enthusiastic and self-driven scientists to participate in a joint venture between Astra Zeneca and Promega. You will spend 2 years at the Astra Zeneca R&D site in Gothenburg, Sweden, with the possibility of additional 6 months at the Promega headquarters in Madison (WI), USA. This is a unique opportunity to fully experience a global research environment and contribute to active projects under the mentorship of leading genome experts.

As a Postdoctoral Fellow in the Astra Zeneca/Promega joint venture, you will be part of a group of passionate researchers who are dedicated to innovation and the advancement of science. Our focus lies primarily in the creation and application of enabling technologies that advance our understanding of fundamental biological processes and aid in the development of novel therapeutical approaches.
You will lead an independent project in a supportive and team-oriented environment, and you will be able to take advantage of facilities equipped with state-of-the-art instrumentation.

Essential Requirements
  • Ph D degree in molecular/cell biology/genetics
  • Broad multidisciplinary experience and meticulous scientific knowledge
  • Strong cell and molecular biology skills with an advanced understanding of genetic engineering and CRISPR-Cas9
  • Outstanding work ethics with patience, discipline, the desire to work hard, perseverance and the ability to develop and follow a plan
  • A history of previous competitive success

Desirable Requirements
  • Understanding of directed evolution and/or targeted mutagenesis systems
  • Expertise in Next Generation Sequencing and data analysis, and hands on experience with dd PCR and FACS
  • Working knowledge of state of art tools for in silico structure analysis
  • Previous expertise with HSPC, i PSC or primary cells engineering

Why Astra Zeneca?
At Astra Zeneca, we are a global, science-led biopharmaceutical company and our innovative medicines are used by millions of patients worldwide. Our aim is to find solutions that prevent, treat and even cure some of the world’s most complex diseases. We are reshaping our organization to thrive in a complex and ever-changing world. Evolving to become a learning organization – ready and equipped to embrace the challenges and seize the opportunities that lie ahead. We are committed to leading the quest to meet rising global demand for effective healthcare.

So, what’s next?
Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you. Welcome with your application (including CV and cover letter) no later than October 11, 2024. In the event, that we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.

For more information and/or questions, please reach out to hiring manager Marcello Maresca at marcello.maresca@astrazeneca.com.

Find out more
Astra Zeneca Genome Engineering: https://www.astrazeneca.com/what-science-can-do/topics/next-generation-therapeutics/novel-gene-editing-efficient-route-gene-therapies.html#
Life at Astra Zeneca: https://careers.astrazeneca.com/life-at-astrazeneca
This is what we’re made of: https://www.youtube.com/watch?v=9Gb XFX29c CI

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