Company describtion

The mission of the Berlin Institute of Health at Charité (BIH) is medical translation: transferring biomedical research findings into novel approaches to personalized prediction, prevention, diagnostics and therapies and, conversely, using clinical observations to develop new research ideas. The aim is to deliver relevant medical benefits to patients and the population at large. Since 2021 the BIH has been integrated into Charité as its so-called third pillar.

For the the group of Prof. Dr. Birgit Sawitzki starting from January 1, 2025 until December 31, 2026 we are looking for a Post Doc (d/f/m) in full-time.

The Sawitzki lab at the Berlin Institute of Health at Charité – Universitätsmedizin Berlin investigates the molecular mechanisms of immune cell activation and regulation, to better understand why components of the immune system become a trigger of destructive inflammatory reactions, like in the context of autoimmune diseases or SARS-Co V-2 infections. We are using especially multi-parametric technologies (cytometry, imaging, sc RNAseq) to uncover pathological changes in the composition and function of immune cells in patient cohorts, which could serve as therapeutic targets.

What you can expect
The candidate will be involved in a project that aims to understand why certain patients develop severe immunopathologies in case of e.g. COVID-19 breakthrough infections. This includes:

• Design, and coordination of patient blood sample analyses, especially of multiplex cytometry, single cell RNAseq and SLAMseq analyses
• Bioinformatic analyses and data interpretation
• Further development of experimental methods
• Design and implementation of supporting mechanistic in vitro experiments
• Close interaction with clinicians, basic and data scientists in the execution of the project
• Presentation of the results to other investigators of the consortium as well as at national and international meetings
• Publication of scientific results

What you bring along

• Ph D, or Research Doctorate in Natural sciences (biochemistry, biology, biotechnolgy, or related fields) or Medicine
• Strong academic background and dedication to translational research especially in the field of immunology
• Scientific curiosity, self-driven, and motivation to perform scientifically rigorous experimental work
• Solid experience in coordinating, performing and analysing multiparameter experiments and single cell RNA analysis
• Solid experience in handling and analysis of high dimensional data using R
• Experienced in data analysis and presentation incl. solid statistical knowledge
• Experienced in the publication of research results
• Very good project and data management skills
• Excellent spoken and written English

What we offer you

• A varied job in a forward-looking research institute
• Pay group E13 TVöD VKA-K. The classification is based on qualifications, the respective experience level is calculated on the basis of professional experience. The annual salary (gross) is stated for a full-time position without special or additional payments. The collective agreement can be found here.
• Additional benefits customary in the public sector (including annual special payment, company pension scheme (VBL), capital-forming benefits)
• Flexible working hours and the option of working remote
• 30 vacation days per year (with a five-day week)
• Various support offers to balance work and family life (childcare, cooperation with voiio)
• Very good training and further education opportunities
• Mobile citizens' office on site
• Corporate benefits (travel, leisure, shopping, etc.), Charité Gympass, bicycle leasing or abonnement (Job Rad, mylo)
• Very easily accessible and attractive workplace at the
  Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin

We live diversity!
We welcome applications from people with diverse backgrounds, regardless of gender, nationality, ethnic and social origin, religion and ideology, disability, age, sexual orientation and identity. Applications from women are expressly encouraged. Severely disabled and equivalent applicants will be given special consideration if they have the same qualifications and suitability.
We believe that diverse teams representing a wide range of experiences, perspectives and backgrounds enrich our research and work.
Please submit your application via our online application form with a letter of motivation, curriculum vitae (without photo, without age statement and without information about your marital status) and other relevant attachments (such as employer references, degree certificates, etc.) by October 21, 2024, quoting the reference number 3817.
Proof of measles immunity / measles vaccination is a prerequisite for employment for those born after 1970.
You can find more information about BIH here.

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