About us

Background

The position

Tasks and responsibilities

• Characterisation of transcription factor assemblies using both bulk assays (fluorescence microscopy, scattering) and single-molecule assays (optical tweezers and DNA curtains)
• Generation of different DNA substrates
• Recombinant expression and purification of proteins
• Analysis and documentation of all data generated
• Regular participation and presentation at CRC1551 events which involves presenting to and discussing with scientists from other disciplines (physics, chemistry, computational biology)
• Regular participation and presentation in meetings at IMB and in conferences
• Study of relevant scientific literature

Requirements

• Highly motivated and creative researcher who enjoys multi-disciplinary science and single-molecule studies
• Recently completed Ph D in biochemistry, structural biology or related discipline
• Strong background in biochemistry and biophysical assays
• Ability to work closely with scientists outside your field (esp. physicists)
• Experience in recombinant expression and purification of proteins as well as cloning
• Ability to work precisely and good attention to detail
• Ability to work independently as well as in a team
• Willingness to learn new skills
• Very good oral and written communication skills in English
• Experience in the following is desired:
  • working in an inter-disciplinary environment
  • using optical tweezers or other single-molecule technique
  • experimentation with IDR-containing proteins
  • fluorescence microscopy
  • python (or other language) for data analysis
  • background in the regulation of gene expression

Why join us?

We offer a stimulating, diverse and international research environment, with a pleasant working atmosphere, and informal culture. The institute is modern, well-equipped and centrally located with good public transport links and parking. Integration within the CRC1551 offers a stimulating scientific environment on campus with many events relevant for your research and career progression.

Our offer

• Competitive salary and favourable pension scheme
• Advanced training opportunities
• Flexible working hours
• Employee events
• Job Ticket

Benefits due to the integration into the CRC1551 (more info about CRC1551 here):

• Annual meeting
• Additional travel money
• Optional Winter School
• Joint meeting with SPP2191
• Outreach activities
• Mentorship program
• Additional training opportunities
• Regular seminars with world class speakers highly relevant to your field of research.

What else you need to know

• Starting Date: February 2025 or later
• Duration: initially 2 years with possibility of extension
• Deadline: 15th December 2024
• International applicants: we will assist you through the visa process, and also with your application for a residence/work permit after your arrival in Mainz.

Have we sparked your interest?

To apply, please upload your application containing your cover letter, CV, certificates and contact information of at least two professional references to our application form. Should you have any questions regarding the application process, please contact us by email hr@imb-mainz.de, quoting Ref. No. #SWPD01. Informal enquires should be addressed to Dr Sina Wittmann. IMB is an equal opportunity employer.