IRCCS San Raffaele Scientific Institute in Milan is looking for a Pre-doctoral Research Fellow to join the Human Inherited Neuropathy Unit, led by Prof. Alessandra Bolino.
The research fellow will contribute to a preclinical gene therapy project based on AAV (Adeno-associated viral vector) delivery aimed at preventing very severe forms of demyelinating neuropathies with infantile onset in human. The fellow will work on a highly translational project in the San Raffaele campus, which provides the unique opportunity to conjugate clinical and basic research. Our laboratory collaborates with the Department of Neurology of the Hospital and participates to established national and international clinical networks on these diseases.

Main activities:
AAV vector cloning
Primary cell transduction
AAV9 delivery in vivo in animal models of CMT
Vector biodistribution by real time PCR analyses (VGCN)
Quantitative m RNA analysis
Biochemical analyses (biomarker analysis)
Immunohistochemistry on tissues
Morphological analyses of the peripheral and central nervous system
Behavioral studies

Who we are looking for:
The candidates hold a Life Science degree
Highly motivated candidates who wish to be enrolled in a Ph D training program in the next years
Ability to work in team; research planning and organization, and communication skills are required

Work details:
Type of contract: collaboration full time
Immediately available
Place of work: IRCCS San Raffaele Hospital, Via Olgettina, number 60 - Milan (Italy)

At San Raffaele Scientific Institute, a world-renowned center of excellence for clinical and scientific activities, we believe that considering diversity and promoting an open and inclusive environment is crucial to our success. We are committed to ensure that equal employment opportunities are provided and based on merit without regard to age, religion, sex, disability, medical condition, sexual orientation, cultural and social backgrounds, gender identity or expression, national or ethnic origin, or any other legally recognized status entitled to protection under applicable laws. We offer attractive conditions and rewards appropriate to an internationally competitive research organization.