Job Description

We are seeking a highly motivated and detail-oriented Research Assistant to join our team at the forefront of i PSC biobanking. The successful candidate will play a pivotal role in the collection, characterization, and maintenance of induced pluripotent stem cell lines, contributing directly to cutting-edge research initiatives in regenerative medicine, disease modeling, and drug discovery.

Responsibilities

1. i PSC Reprogramming

• Execute established protocols for the reprogramming of i PSC lines.

• Collaborate with researchers to further optimize workflow for reprogramming.

• Explore alternative workflows for reprogramming.

2. i PSC Culture and Maintenance:

• Execute established protocols for the culture and expansion of i PSC lines.

• Monitor cell growth, viability, and quality control parameters.

• Perform routine passaging and cryopreservation of i PSCs.

• Maintain accurate records of cell culture activities.

3. i PSC Characterization:

• Conduct immunocytochemistry, flow cytometry, and molecular biology techniques to assess pluripotency and differentiation potential of i PSC lines.

• Perform karyotyping and other cytogenetic analyses to ensure genomic stability.

• Collaborate with researchers to design and implement experiments for i PSC characterization.

Responsibilities

4. Biobanking Operations:

• Coordinate sample collection, processing, and storage according to standardized protocols.

• Label, track, and catalog i PSC samples in the biobank database.

• Implement quality control measures to ensure sample integrity and compliance with regulatory

requirements.

• Assist in the development and optimization of biobanking workflows.

5. Data Management and Analysis:

• Compile and organize experimental data, including cell culture records, characterization results, and

biobank inventory information.

• Analyze data using statistical methods and assist in the preparation of research reports and

presentations.

• Contribute to the maintenance and updating of laboratory databases and electronic notebooks.

Responsibilities

6. Laboratory Support:

• Maintain cleanliness and orderliness of the laboratory.

• Assist in the procurement and organization of laboratory supplies and reagents.

• Support other members of the research team in experimental procedures and technical troubleshooting.

Qualifications

• Bachelor's in Biology, Biochemistry, Molecular Biology, or a related field.

• Hands-on experience in cell culture techniques, preferably with human pluripotent stem cells.

• Familiarity with basic molecular biology and cell biology techniques (e.g., PCR, Western blotting, immunocytochemistry).

• Strong organizational skills and attention to detail.

• Ability to work independently as well as part of a collaborative research team.

• Prior experience in biobanking or sample management is advantageous.

• Knowledge of relevant safety protocols and regulatory guidelines in cell culture and biobanking is desirable.

This position offers an exciting opportunity to contribute to groundbreaking research in i PSC biology and biobanking, with potential for career development and growth within our dynamic research environment.

More Information

Location: Kent Ridge Campus
Organization: Yong Loo Lin School of Medicine
Department : Medicine
Employee Referral Eligible: No
Job requisition ID : 26693