Responsibilities and Duties

• Perform in vivo experiments to assess the expression, efficacy, safety and mode-of-action of etherna’s m RNA immunotherapies.
• Independently plan and execute in vivo and ex-vivo experiments, upon approval
• Mice manipulations including injections (intramuscular, intravenous, intraperitoneal, subcutaneous), blood collection, weight measurements, muscle swelling, and in vivo imaging, organ dissection and ex-vivo imaging
• Generation and characterization of formulations for m RNA delivery
• Analysis of harvested cells and biological materials using techniques such as flow cytometry, ELISA, ELISPOT
• Cell culture of murine cell lines and primary cells required for ex-vivo assays (including splenocytes, PMBCs, bone marrow cells)
• Assist in the development of new assays, including optimizations and writing/adjustment of protocols and SOPs
• Compile and analyze data to assist and present in project team or other internal meetings and maintain a detailed electronic lab book related to ongoing experiments
• Assist in keeping track of relevant advancements in the field by means of literature search
• Assist in maintaining a clean and tidy lab environment and share common maintenance tasks, including the animal facility

Education

• Professional bachelor’s degree in biomedical laboratory Techniques or master’s degree in biomedical sciences/Biotechnology or related field or equivalent relevant laboratory experience
• FELASA B/C certified

Experience

• Prior experience in in vivo studies and animal handling is mandatory
• Preferably 1-2 years of relevant experience in a research environment focused on biotechnology, biology, immunology or related field, either in academia or biotech
• Experience with the culture of cell lines for in vivo models and with immunological assays is a plus
• Experience with flow cytometry is an advantage
• Basic knowledge of statistics is preferable
• Animal colony management experience (and knowledge of colony management software) is an advantage

Other qualifications and skills

• Detail-oriented and accurate in following instructions, record keeping and completion of reports
• Able to perform experimental troubleshooting and to propose technical solutions
• Scientific integrity
• Good communication skills
• Well organized, well-structured, hands-on, result focused
• Able to work under stringent timelines
• Ability to foster teamwork and a collaborative atmosphere. Ability to work effectively both independently and as part of a team with multiple cultural backgrounds
• Enthusiastic, flexible and able to multitask. Flexibility dealing with changing priorities and the capacity to continuously prioritize is required
• Proficient in written and spoken English
• Knowledge of MS Office (Excel, Word, Power Point, Outlook) and Prism

• An exciting job in a dynamic and entrepreneurial environment with room for personal development.
• Work within an innovative environment where you can learn a lot.
• Employment contract of unlimited duration with a competitive salary package.
• Working in a fun team where collaboration, growth but above all fun are central.