1x funding 18 month Limited Appointment/Project, at will appointment.

The successful candidate will perform research in antibody engineering and functional characterization. Tasks include phage and yeast antibody library selection, protein production and purification from bacteria and mammalian cells, confocal microscopy, and bio-layer interferometry.

Under direct supervision with training provided, the position is assigned to assist in identification and characterization of novel tumor cell surface antigens, identification of human monoclonal antibodies binding to those antigens from phage and yeast antibody display libraries, and antibody-based therapeutic development.

Responsibilities:

• Confocal microscopy analysis
• Molecular biology including PCR, gene cloning, plasmid construction and purification
• Microbiology including bacteria and yeast culture, transformation, and selection
• Antibody (sc Fv and nanobody) cloning, expression, purification, and analysis
• Antibody affinity and specificity analysis by label free methods
• Antibody selection output analysis by deep sequencing
• Maintenance of mammalian cell culture and tissue culture

The final salary and offer components are subject to additional approvals based on UC policy.
Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.
The salary range for this position is $26.00 - $31.04 (Hourly Rate).
To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

The Department of Anesthesia and Perioperative Care at UCSF provides outstanding patient care, promotes cutting-edge basic and clinical science research, and educates the next generation of health care providers while focusing on increasing diversity, equity, and inclusion across the organization.

The Department of Anesthesia and Perioperative Care ranks as one of the largest departments in the School of Medicine with an annual budget of $145 million. The two largest components of the annual budget are Professional Fee Income and Extramural Funds, representing 90.4% or $132 million (including ZSFG professional fees and 6.9% or $10.1 million of the annual budget respectively. Currently, the department has over 298 Faculty members, 27 Staff Physicians, 205 Staff Employees, 6 Fellows, 90 Residents, 12 Non-Faculty Academics, 11 Post Docs, 68 CRNAs and 5 Nurse Practitioners at ZSFG.

In addition to the Moffitt-Long Hospital, very active units of the department exist at the Zuckerberg San Francisco General Hospital and Trauma Center (inpatient and outpatient, including a very active trauma service), San Francisco Veterans Affairs Medical Center (inpatient and outpatient), Mt. Zion Medical Center (outpatient, including 23 hour stays and the Pain Management Center), Benioff Children's Hospital Oakland, the UCSF Orthopedic Institute and the Benioff Children's, Betty Irene Moore Women's and Bakar Cancer (NIH-designated Cancer Center) Hospitals in the Mission Bay neighborhood.

The Department now has essential roles in patient care outside of the operating rooms, with active participation in Ambulatory Care, Acute and Chronic Pain, and in the Preoperative Clinic. Over the department’s fifty-plus years of existence, the department has been at the heart of modern anesthesia’s explosive growth, and to this day continues to have an enormous impact on surgical practice and the management of pain. The department’s research, education, and clinical care quickly earned and have maintained reputations that are the equal or better of any institution in the world. Individual members of our faculty have had a major influence on our specialty both nationally and internationally, including NIH study sections, NIH funding, FDA and Editorial Boards. Research activities within this department are integrated with and inform clinical practice. For many years, ours has been among the top departments for NIH research funding in anesthesia in the United States.

The Department of Anesthesia provides considerable support and structure for research in general and, for research training programs, highlighted by the innovative Pathway to Scientific Independence (PSI). This program begins at the residency level, incorporating the Research Scholars Track of the Anesthesia Residency, moving through the post-residency NIH-funded T32 training grant, and faculty positions with a mentored research support, and ultimately to achieving extramurally funded, independent researcher status.

• BA/BS in a related science and knowledge of, or experience with, the basic techniques or methods required by the position; or an equivalent combination of education and experience;
• Familiarity with techniques commonly used in molecular biology and protein chemistry labs
• College coursework in molecular biology, biochemistry and computer sciences

• Confocal microscopy
• Molecular biology including PCR, gene cloning, plasmid construction and purification
• Microbiology including bacteria and yeast culture, transformation, and selection
• Antibody (sc Fv and nanobody) cloning, expression and purification
• Antibody analysis by SDS-PAGE, Western blot, FPLC and HPLC, label free methods (e.g., BLITZ or Bia Core), ELISA, and flow cytometry
• Antibody selection output analysis by deep sequencing
• Maintenance of mammalian cell culture and tissue culture
• Working knowledge of safety standards in laboratories

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Campus

009613 SRA 1

Research and Scientific

University Professional Technical Employees – Research Support Professionals Unit (UPTE-RX)

Limited Appt

100%

Zuckerberg San Francisco General (ZSFG)

Days

8 Hours

M-F, 40 hrs/week