Post-Doc position in Single Molecule Localisation Microscopy and Spectroscopy
- (2400008H)

Commitment & contract: 1 Year + 1 Year Contract
Location: IIT Erzelli, Genova

WHO WE ARE
At IIT we work enthusiastically to develop human-centered Science and Technology to tackle some of the most pressing societal challenges of our times and transfer these technologies to the production system and society. Our Genoa headquarter is strictly inter-connected with our 11 centers around Italy and two outer-stations based in the US for a truly interdisciplinary experience.

THE PROJECT
The Single-molecule localization microscopy (SMLM) is a powerful imaging technique that significantly enhances spatial resolution beyond the diffraction limit of traditional microscopy. This breakthrough enables the visualization of biological structures at the molecular scale. Importantly, structural information obtained through SMLM can potentially be correlated with functional molecular-scale data by combining imaging with spectroscopy, such as fluorescence lifetime or emission spectrum analysis.
Recently, the development of novel single-photon detector arrays, specifically single-photon avalanche diode (SPAD) arrays, has opened new avenues for integrating single-molecule localization microscopy with advanced spectroscopic capabilities.
In this context, we invite applications from motivated and talented postdoctoral researchers to join the Molecular Microscopy and Spectroscopy Research Unit at IIT, led by Dr. Giuseppe Vicidomini.
The project focuses on developing innovative single-molecule localization techniques for combined structural and functional imaging, leveraging state-of-the-art SPAD array detectors.
The successful candidate will play a key role in designing optical microscopy systems and developing methods for data analysis. Additionally, the Postdoc will collaborate with the RNA Technology Flagship to apply these advanced assays to RNA biology, shedding light on RNA’s role in biomolecular condensates and their functions.

RESPONSABILITIES

• Design and build the advanced optical microscopy architecture for single-molecule localization and spectroscopy.

• Develop and implement innovative methods for data analysis to extract structural and functional molecular information.

• Work closely with the RNA Technology Flagship to apply developed assays to RNA biology.

• Support the development of junior researchers by mentoring Ph D students and interns involved in related projects.

• Publish findings in scientific journals and present results at national and international conferences.

REQUIREMENTS

• A Ph D in Physics or related disciplines;

• Experience in fluorescence microscopy;

• Experience in analyzing microscopy data;

Expertise in single-molecule techniques and related data analysis;

• Good record of publications in top tier conferences/journals in the field of photonics and/or biophysics;

• Strong problem-solving attitude;

• Strong Programming skills (Python, etc.);

• The ability to properly report, organize and publish your research results;

• Good command of spoken and written English.

Experience in fluorescence lifetime and emission spectroscopy is highly desirable.

COMPENSATION & BENEFITS

• Competitive salary for international standards;

• Private health care coverage;

• Wide range of staff discounts;

• Candidates from abroad or Italian citizens who have carried scientific research activity permanently abroad and meet specific requirements, may be entitled to a deduction from taxable income of up to 90% from 6 to 13 years.

WHAT’S IN FOR YOU?

• An equal, inclusive and multicultural environment ready to welcome you with open arms. Discrimination is a big NO for us!

• We like contamination and encourage you to mingle and discover what other people are up to in our labs!

• If paperwork is not your piece of cake, we got you! There’s a specialized team working to help you with that, especially during your relocation!

• If you are a startupper or a business-minded person, you will find some exceptionally gifted professionals ready to nurture and guide your attitude and aspirations.

• If you want your work to have a real impact, in IIT you will find an innovative and stimulating culture that drives our mission to contribute to the improvement and well-being of society!

• We stick to our values! Integrity, courage, societal responsibility and inclusivity are the values we believe in! They define us and our actions in our everyday life. They guide us to accomplish IIT mission!

We inform you that the information you provide will be used solely for the purposes of evaluating and selecting professional profiles in order to meet the requirements of Istituto Italiano di Tecnologia. Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security. Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone Tel: +39 010 28961 - email: dpo@iit.it ).

Primary Location GENOVA ERZELLI

Job Postdoc

Organization Molecular Microscopy and Spectroscopy

Job Posting Nov 21, 2024, 8:54:04 AM