Switzerland Job Openings

Paul Scherrer Institut PSI
PhD Student
October 4, 2024
Your tasks
Your tasks will include:
- Evaluate metal elements, metallic nanoparticles in postmortem brain tissues of individuals with neurodegenerative diseases by using X-ray microspectroscopy and energy SEM-dispersive X-ray (EDX) analysis
- Investigate how amyloid proteins, particularly Alzheimer's Aβ and Parkinson's α-synuclein, induce the formation of metallic nanoparticles in coacervation through the use of biophysical techniques such as NMR spectroscopy and X-ray absorption spectroscopy
- Characterize the cellular toxicity and potentially harmful effects of metallic nanoparticles and metal-protein coacervates using cell viability assays and other biochemical assays
- Collaborate with other group members, utilizing the facilities and resources available at the PSI and Biozentrum Basel
- Co-supervise and co-support master and bachelor students
- Present work at international conferences/workshops and publish work
Your profile
- Good background in protein aggregation, amyloid research, or metal-protein interactions
- Experience with biophysical techniques such as NMR spectroscopy or soft Xray absorption spectroscopy
- Knowledge of neurodegenerative diseases and their molecular mechanisms
- Ability to work independently as well as collaboratively in a multidisciplinary team
- Excellent communication and scientific writing skills
We offer
For further information, please contact Dr Jinghui Luo, phone +41 56 310 47 64.
Please submit your application online by 13 October 2024 (including addresses of referees) for the position as a Ph D Student (index no. 2411-00).
Paul Scherrer Institut, Human Resources Management, Luca Simen, 5232 Villigen PSI, Switzerland
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