Switzerland Job Openings

Molecular Partners AG

Research Associate Cell Line Development

Schlieren

September 12, 2024

General information

Reference

2024-166

Information about Molecular Partners AG

Founded in 2004 by a group of Ph D students as a spin-off from the University of Zurich, Molecular Partners AG is a thriving and steadily growing clinical stage biotech company located in Zurich-Schlieren (Switzerland) with 200 highly qualified employees. In order to advance modern medicine and significantly improve the management of serious diseases, we have developed and successfully established a powerful new class of potent, specific and versatile small protein therapies, called DARPin therapeutics. The continuous development of a broad portfolio of therapeutic product candidates in oncology, virology and ophthalmology based on the company’s proprietary DARPin platform allowed a successful listing of the company on the SIX Swiss Exchange and Nasdaq (ticker: MOLN). Next to our own pipeline of drug candidates we have entered into collaborations with leading international pharmaceutical companies, including Abb Vie, Amgen and Novartis. The highly dedicated, multi-disciplined team at MP is committed to developing breakthrough medicines for serious diseases.

Position description

Position title

Research Associate Cell Line Development

Job description

We are seeking a skilled Research Associate to join our Cell Line Development team. This role will contribute technically and scientifically to the advancement of multiple projects, as well as bring innovation to our Cell Line Development team. This diverse position will include the following responsibilities:

Contribute to the maintenance of an internal cell line bank, including banking of new cell lines and ensuring the quality of cell lines for Research purposes;
Develop and engineer new cell lines with different approaches (transfection, lentiviral transduction, CRISPR/Cas9-based techniques);
Assessment and quantification of target antigen expression;
Design and perform cell based assays, such as cell binding, to support DARPin screening and Mode of Action studies;
Contribute to improvement of processes and techniques;
Identify and work with CROs where applicable;
Analysis and interpretation of data and presentation to internal stakeholders;
Maintain a close collaboration with cross-functional project teams;
Maintain accurate and timely up-to-date documentation (e LN, Freezer Works) in English;
Update and optimization of local guidelines / SOPs for the Cell Culture team in English;
In addition, you will contribute to the rotation system for the cleaning and maintenance of the Tissue Culture room, stock refill, PBMC isolation and maintenance and inventory of all the -80°C freezers and Liquid Nitrogen tanks.

Requirements

For this position, we are looking for a highly motivated individual bringing along:

A Master degree in Biology or equivalent;
Previous experience in industry is a plus;
Extensive hands-on experience with mammalian cell culture methods, hands-on work with primary human cells is a plus;
Required hands-on experience in:
- Transfection, transduction
- CRISPR
- Flow Cytometry
Careful and accurate working style, quality awareness;
Full professional proficiency in English;
MS-Office computer skills (Windows, Office, in particular Excel, Word, Outlook and Teams);
Data analytic software, such as Graph Pad Prism;
Freezer Works is a plus;
Flexible and independent working attitude;
Adapts successfully to changing situations and environments;
Strong willingness to learn;
Well-developed communication, team and organizational skills;
Proactive personality and drive to optimize workflows.

This position summary is not intended to be all inclusive. An employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

Our offer

Partnership and collaboration are at the core of our company, our research activities and our product candidates. Molecular Partners offers an international working environment and the opportunity to collaborate with outstanding individuals from numerous disciplines, who contribute to our shared goals of scientific excellence, respectful teamwork and personal aspiration. We foster true innovation and creative thinking to advance our therapeutic product candidates and continue to be inspired by the difference we can make for our patients. At Molecular Partners you will discover a challenging job, inspiring colleagues and a true purpose. If you are interested in working at Molecular Partners, we are looking forward to hearing from you!
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Position location

Job location

Switzerland, Zürich, Schlieren

Preferred head hunter clause

Please note Molecular Partners AG operates a list of preferred recruitment partners. For those partners who have no valid, signed agreement in place with Molecular Partners AG, all unsolicited resumes, CVs, anonymous profiles, or any other candidate details submitted through our website or to personal e-mail accounts of employees of Molecular Partners AG (including any of its subsidiaries, affiliates or related companies) are not subject to payment of any form of introduction, placement or referral fees.

Molecular Partners AG, Wagistrasse 14, CH-8952 Zurich-Schlieren, Switzerland.
www.molecularpartners.com

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