Careers at Valerius Biopharma, committed to providing specialty biosimilar
drugs globally

Are you looking to making a difference?

Valerius Biopharma AG is a biopharmaceutical company in Switzerland, established to provide
affordable treatment options for high-priced biologics through development of specialty biosimilars. Our
interdisciplinary team of professionals represents decades of experience gained in the biotechnology
and biosimilar industry. Expertise in process science, a deep understanding of proteins and their
underlying complexity, as well as skilled clinical and regulatory expertise, are key factors to our success.
We are committed to making treatment of severe and life-threatening diseases more accessible to all
patients worldwide.

For our emerging development hub in the south-east of Belgium (Eupen/Liège) we are seeking highly
skilled and motivated associates to join us in building a world leading center for specialty biosimilar drug
development.
Activities and responsibilities
Primary objectives & goals
The Head Upstream Process (USP) is leading the USP team and designs, executes and interprets
experiments to set up the development of cell lines and cell banks, the fermentations and all related
processes, and manages the associated infrastructure including the according documentation
(protocols, reports, SOPs), batch releases of raw material, material shipments, and laboratory
equipment monitoring.
Scope & Responsibility

• Lead and manage the USP team.

• Represent USP for the assigned portfolio at management and external stakeholder levels.

• Oversees all USP programs and projects, guides teams to ensure cross-functional integration,

coordination and alignment.

• Ensures direct reports are actively and appropriately aligning with other teams to ensure timely and

on-target results.

• Provides leadership guidance and direction in ongoing enhancements/development of core and

sub-team processes, structures, systems, tools and other resources.

Overall team’s responsibility:

• Support establishment of new platform technologies for high throughput upstream process

development using mammalian cell cultures.

• Design, plan, organize, execute and analyse experiments to develop and execute the transfer (scale

up) of processes in to production facilities.

• Supports the development of new experimental approaches and related work processes and

procedures that align with company and regulatory requirements.

• Conduct test runs.

• Keep records in electronic laboratory notebooks, and authoring of procedures, protocols, technical

reports, standard operating procedures (SOPs) and presentations.

2

• Release batches, organize and oversee shipments to and from external stakeholders, support

Clinical Study logistics.

• Operate Upstream Process GMP production.

Qualification profile
Desired Professional and Technical Requirements
Education/Qualifications

• Completed studies, preferably MSc or Ph D, in Biotechnology, Biology, Chemistry, Engineering, or a

comparable degree with corresponding professional experience.Experience, Skills, Knowledge

• At least 4-year experience in upstream process development and manufacturing techniques.

• Strong track record with mammalian cell cultures (e.g. CHO, SP2/0) and knowledge of cultivation

techniques.

• Experience with single-use bioreactors from m L-scale to 200 L production scale favourable

• Leadership/management experiences.

• Knowledge of biopharmaceutical active substance production and analytics.

• Good knowledge of English written and oral.
  

Contact
Please send your application to:

Valerius Biopharma AG

Norbert Bleich
Stänzlergasse 4
CH-4051 Basel
Phone: +41 61 205391-334
application@valeriusbio.com