A Technician position is available in the TIGET Clinical Lab (TCL) coordinated by dr. Matias Soncini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, Italy.

The Institute. SR-Tiget was created in 1995 as a joint venture between Fondazione Telethon and Ospedale San Raffaele (OSR), with the mission to perform cutting-edge research on gene and cell therapy and to translate its results into therapeutic advances for genetic diseases. The Institute is located within the OSR campus, which includes a large multi-disciplinary research hospital, a biomedical research center, a university and also hosts several biotechnologies companies. Over the years, SR-Tiget has given a pioneering contribution to the gene and cell therapy field with relevant discoveries in vector design, gene transfer and gene editing strategies, stem cell biology, identity and mechanism of action of regulatory cells in immune responses and innate immune cells in cancer. SR-Tiget has also established the resources and framework for translating these advances into novel experimental therapies and has implemented several successful gene therapy clinical trials, which have already treated >120 patients and led to the filing and approval of novel advanced therapy medicines.

The position. We are looking for a motivated technician to work in TCL, which is part of the development units of SR-TIGET. TCL is a clinical research laboratory that analyzes samples from patients who underwent experimental Cell and Gene Therapy (CGT). TCL is an AIFA autocertified Phase I laboratory where the biological effects of experimental CGT are studied following approved Clinical Protocols and in compliance with Good Clinical Laboratory Practice (GCLP).

Main tasks:
Direct involvement in wet lab activities;
Managing and tracking of biological samples following GCLP principles;
Compiling all the Quality documentation related to the laboratory activity;
Collaboration in the preparation of Standard Operative Procedures.

Basic Qualifications and Skills:
Scientific bachelor’s or master’s Degree with wet lab experience;
Experience in ex-vivo cellular biology
Experience in cytofluorimetric analysis is a plus;
Experience in molecular biology (q PCR, dd PCR);
High accuracy, reliability, precision;
Ability to work autonomously;
Ability to prioritize and manage multiple tasks;
Friendly, collaborative, pro-active mindset;
Good oral and written English;
Plus: Experience in GXP laboratories: ALCOA data recording, SOP, Non-Conformity, CAPA management.

We offer;
Competitive salary depending on qualifications and experience;
A dynamic environment and the chance to make an important contribution to the clinical translation of innovative Advanced Therapies (ATMPs)