Postdoctoral Fellow - Haase lab - Spain Job Openings

Spain Job Openings

European Molecular Biology Laboratory

Postdoctoral Fellow - Haase lab

Barcelona

September 10, 2024

Postdoctoral Fellowships
Barcelona, Spain

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organizations in the world. The newest EMBL site is located in the Barcelona Biomedical Research Park (PRBB), one of the largest infrastructures in Southern Europe dedicated to translational research. The main focus of the EMBL Barcelona site is in tissue biology and disease modelling.

The Postdoctoral Fellow position will support the project ¨A novel Maternal-Fetal-Interface on-Chip for Human Investigation of Placental exposures and infections (MFI-CHIP)¨ with the contract as part of the grant PID2023-152966NB-I00, funded by MCIU/AEI/10.13039/501100011033 and by the ESF+.
The Haase lab´s main interest is in developing tissue-specific 3D in vitro vascular models that recapitulate developmental and diseased vascular phenotypes. Our unique tissue-engineering approaches allow us to generate human microvessels with in vivo-like characteristics. As part of the MFI-CHIP grant we aim to further develop a novel 3D vascularized maternal-fetal interface to represent late-stage of the placental barrier. Specifically, we aim to investigate the impact of sex differences, hormones, and exposures on transport across this critical placental barrier.

Your role

We are looking for an extremely motivated candidate who will take on this cutting-edge project, which has translational potential. The successful candidate will learn, from a current senior team member, how to setup the 3D culture of an in vitro maternal-fetal interface on-chip. The candidate will become adept at employing the model and all associated assays and analysis techniques. As part of a collaboration with local clinical researchers, the candidate will isolate primary-derived trophoblast cells from explanted placenta for incorporation and optimization on-chip. Once optimized, the model will be used to explore a range of questions

You have

A Ph D in biology, bioengineering or related fields, preferably worked with 3D cell culture
Extensive experience working with primary-derived human cells
Strong practical skills in cell culture and molecular biology techniques
3D tissue culture experience
Advanced microscopy and quantitative imaging skills
Experience with bulk RNAseq analysis
Independent and motivated work habits
Excellent verbal and written communication skills in English
Excellent organization and time management skills are a must
Strong interest in the maternal-fetal interface and its dysfunction in humans

You might also have

Knowledge of vascular and/or placental biology
Worked with cell isolation techniques from explant tissue (placenta)
Hands-on experience with microfluidics and microfabrication techniques (3D printing, working with PDMS devices)
Experience in advanced image analysis or computational skills (Image J, Python)

Why join us

EMBL offers a highly collaborative and uniquely international working environment. We foster top quality, interdisciplinary research and expect that this individual will bridge research groups across EMBL Barcelona and our local clinical collaborators. EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization with a very collegial and family friendly working environment. EMBL is committed to internationality, diversity and equality, and as such encourages applications from underrepresented groups.

What else you need to know

We are Europe’s research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1900 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.
**Don’t meet every single requirement? We are dedicated to building a diverse, inclusive and authentic workplace, so if you’re excited about this role but your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply nevertheless.
EMBL is a signatory of DORA. Find out how we implement best practices in research assessment in our recruitment processes here.
Further information about research at EMBL Barcelona can be found at www.embl.es.
This Postdoctoral fellowship contract is part of the grant PID2023-152966NB-I00, funded by MCIU/AEI/10.13039/501100011033 and by the ESF+.

We regret to inform you that this job opportunity is no longer available as it has expired

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