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Roche
Principal Quantitative Scientist, RWD
Zug
FULL TIME
October 31, 2024
As a Principal Quantitative Scientist, you are responsible for leading, conceptualizing, planning and executing advanced real-world data (RWD) projects to generate evidence in support of the CDS portfolio, clinical tests, diagnostic devices, and services developed and marketed by Roche Diagnostics.
The data you will be working with are varied in type including clinical patient-level data, supplemented with data such as omics, imaging, digital health, etc.
You will collaborate with peers within the function and across the organization to develop and improve existing strategies, CDS and workflow solutions, improve product support strategies, identify evidence gaps and data sources, design and execute studies, implement analyses to support improvement of existing products, and lead discovery and early development of new features or apps to drive the NAVIFY portfolio as well as Diagnostics clinical tests, devices, and services.
You will be able to quantify the value of these products from both a patient outcome, business value, as well as from a regulatory perspective.
You will drive creation of best practices and share learnings/experience with colleagues both internal and external to the function to shape the use of RWD and implement sustainable, science-based practices in Diagnostics.
In this position, you will also ensure that the design, execution, and presentation of evidence are adhering to the highest scientific standards. In order to succeed, you will leverage your expertise and expand knowledge of available healthcare data sources and applicable state-of-the-art methodologies.
Hands-on experience collaborating with and leading team members who have large scale data processing and visualization, and languages and tools (R, Python, (no-)SQL, Hadoop, Spark, etc.) is required.
In addition, you will rely on your scientific expertise, and your ability to interact and influence cross-functional experts such as biostatisticians, epidemiologists, product owners and oncologists, to discover novel insights demonstrating impact of various treatment decisions, and uncover key elements leading to best outcomes for patients.
This role is hybrid with a physical presence at one of the following Roche campuses: Santa Clara, CA; Basel, Switzerland; or Rotkreuz, Switzerland. .
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Provide RWD leadership for evidence generation using RWD, supporting In-Vitro Diagnostics (IVD) and CDS product portfolio at Roche Diagnostics.
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Contribute to the primary strategic and operational responsibility for the design, execution, and reporting of RWD studies using a variety of available research and commercial healthcare databases.
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Identify and establish collaborations with healthcare institutes expanding sources of available RWD sources.
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Work closely with clinical development, operations, and medical affairs directors across Roche Diagnostics to create, confirm and validate disease & clinical hypotheses for RWD projects supporting commercial, market access, medical and regulatory needs.
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Promote the increased adoption and use of RWD to supplement clinical study design and execution, and identify opportunities where RWD could be the primary evidence generation mechanism to achieve regulatory and reimbursement objectives for IVD and CDS products being developed across Roche Diagnostics.
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Develop RWD study protocols and lead analysis projects supporting evidence needs of IVD and CDS product portfolio. Collaborate with internal and external partners (e.g., key opinion leaders, academic institutions, CROs) on the design and implementation of RWD studies.
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Ph D (preferred) OR Master’s Degree in a Quantitative science related field (e.g. Pharmacoepidemiology, Epidemiology, RWD Biostatistics, Pharmacoeconomics, Health Economic and Outcomes Research) and 8+ years of direct related experience.
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Background in biology or medicine, either through education or professional experience.
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Strong experience in using research and commercial RWD sources, national and regional disease data registries.
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Proven hands-on experience in generating new hypotheses, extracting/managing big data sets, design, implementation and reporting of RWD studies, in the Diagnostics/Pharma industry.
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Understanding of regulatory guidelines for Diagnostics/Pharma.
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Expertise in national and international coverage policies and proven experience in the use of RWD to influence reimbursement and clinical guidelines.
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An expert in RWD analysis. Equipped with hands-on experience in data science and a passion to make a difference in healthcare.
Roche Diagnostics International in Rotkreuz is a leading provider of diagnostic systems solutions, and the largest manufacturer of fully automated in vitro diagnostic systems in Switzerland. We are more than 2’700 passionate colleagues from over 65 nationalities. Find out more about our site in Central Switzerland, here.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
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