United States Job Openings

The Ohio State University Wexner Medical Center

Research Senior Associate

Columbus

October 26, 2024

The Ohio State University Comprehensive Cancer Center (OSUCCC) – James is the only cancer program in the United States featuring a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities. The Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels — from prevention to treatment and survivorship. Join our team!

Dr. Glen N. Barber in the OSUCCC-PIIO is looking to hire an enthusiastic, self-motivated Research Senior Associate to contribute to cutting-edge research. Projects in the Barber Laboratory include studying the innate immune regulator STING and its role in influencing inflammatory diseases as well as cancer, particularly the evaluation of novel STING-dependent adjuvants for the immunotherapeutic treatment of cancer. Additionally, they are developing new vaccine concepts to prevent infectious diseases and cancer.

The Barber Laboratory also works in the field of viral oncolysis, specifically the development of a novel vaccine to prevent and possibly treat Human T cell leukemia virus type-1 (HTLV-1) associated diseases. This work involves performing experiments related to viral oncolytic therapies, manipulating and producing recombinant VSV vaccines, testing vaccination regimens, conducting T-cell proliferation assays, and performing antibody neutralization experiments using various mouse models.

Key Responsibilities:
  • Design and perform independent research in innate immunity and inflammation.
  • Collaborate with other researchers and laboratory staff on ongoing projects.
  • Analyze and interpret experimental data and prepare manuscripts for publication in peer-reviewed journals.
  • Maintain detailed and accurate records of experiments and procedures.
  • Present research findings at internal meetings, seminars, and scientific conferences.
  • Stay current with relevant scientific literature and advancements in the field.

Minimum Qualifications:
  • Master's Degree in Microbiology, Immunology, Molecular Biology, or Cancer Biology or equivalent experience required; Ph D preferred.
  • 4-5 years of relevant experience required; 5-7 years of relevant experience preferred.
  • Strong experience with cell culture and molecular biology techniques, including DNA and RNA purification, cloning, q PCR, DNA and si RNA transfection protocols, ELISA, Western Blot, immuno-precipitation, post-translational regulation, cell signaling, immunohistochemistry, and flow cytometry.
  • Experience with animal experiments and a strong understanding of immunology.
  • Strong analytical skills and the ability to work independently.
  • Ability to convey information effectively and follow verbal and written instructions.

Function: Research and Scholarship
Sub Function: Research
Career Band: Individual Contributor - Specialized
Career Level: S2
About Us: The PIIO (Learn more about PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels — from prevention to treatment and survivorship. With more than 100 investigators, the overall ambition of the PIIO is to be a leader in driving immuno-oncology (IO) breakthroughs in systems immuno-oncology, immunogenomics, cell therapy, and translational immuno-oncology.

About Columbus: Columbus, Ohio is the state capital and the 14th largest city in the United States. Columbus is a friendly Midwestern town with metropolitan style. It has been dubbed one of the top ten best cities to live by Money Magazine. With an open-minded approach to life, business, and ideas, Columbus has cultivated a unique environment of thriving communities, companies, institutions, and entertainment. It is a great place to live and has one of the strongest economies in the United States, with easy commutes and a low cost of living relative to comparable metropolitan areas. The city is renowned for its leading technological companies, vast academic resources, thriving industry, an eclectic mix of entertainment, dining, and shopping, and easily accessible opportunities for sports and recreation for participants and fans alike (Learn more about Columbus).

Pay Range:
$55,100 - 72,400 per year.
Term (Fixed Term) 40 First Shift
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