Czech Republic Job Openings

Přírodovědecká fakulta JU

PhD position in Biochemistry/Biology

FULL TIME

October 21, 2024

Přehled
Project title: The Effect of selected arthropod´s compounds on wound
healing
We are looking for 2 motivated Ph D students for a joint research project of
the team Dr. Zdeněk Franta, Ph.D. and doc. RNDr. Jindřich Chmelař,
Ph.D.,the Faculty of Science, University of South Bohemia, the Biology
Centre of Academy of Science of the Czech Republic and the
biotechnology company Contipro a.s.
Project introduction: Natural resources represent one of the main trends
in the search for new medicinal substances. In this research project, we
focus on the identification of new biologics from two organisms that have
evolved unique molecular mechanisms possessing intensive effects on the
mammalian immune system, including human. The larvae of the green
bottle fly Lucilia sericata have been approved as an alternative treatment for
chronic and hard to heal wound, and its excretory and secretory products
contain many substances that facilitate the removal of necrotic tissue and
promote healing. The hard tick Ixodes ricinus produces hundreds of
pharmacologically active substances with anti-haemostatic, anti
inflammatory and immunomodulatory properties in its saliva into the host.
Within this research project, various recombinant proteins from fly larvae
and tick saliva will be produced and subsequently tested in a series of in
vitro and in vivo experiments to find an effective treatment for chronic
wounds.
Student Requirements:
– Mgr/Msc degree in biology, biochemistry or related fields
– hands on experience in molecular and cell biology, biochemistry
and/or immunology.
– the experience with recombinant protein production and purification
advantageous.
– independent and responsible approach to solving complex
questions.
Project job description:
– preparation of recombinant proteins
– protein testing using biochemical, molecular biological and
immunological methods
– working with tissue culture – in vitro models of inflammation
– working with experimental animals (mice) – in vivo models of
inflammation
– bioinformatic analysis of the biologics
We offer:
– work in a young multidisciplinary team, medically oriented research.
– close collaboration with Contipro, a Czech leading biotech company,
possibility of internships
– cooperation with the Biology Centre of Academy of Science of the
Czech Republic
– international cooperation, possibility of internships abroad
– university benefits (5 weeks of vacation, 4 personal sick days per
year, a meal card or the option of meals at the USB canteen at a
reduced price, Childcare benefits, mobile operator benefits, bank
account benefits, language courses)
– competitive Ph D salary (0,5 postdoc FTE) guaranteed for 45
months with possible prolongation
– up to 15 000 CZK scholarship
Position starting: in April 2025 or based on availability
How to apply:
Please submit your application electronically via jobs@prf.jcu.cz until
January 15, 2025.
The application must contain:
– CV
– Contact information from 2 persons for references
More information about faculty at www.prf.jcu.cz.

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