Mission

Tasks and Responsibilities

• In collaboration with senior/principal scientists in the team, identify, evaluate, and probe emerging methods for immune cell isolation, culture, differentiation, and activation.
• Design, execute, interpret, and optimize in vitro assays that can encompass multi-parameter flow cytometry, q RT-PCR, JESS, proliferation, and immunoassays, in order to profile hit, lead and clinical molecules
• In collaboration with senior/principal scientist in the team, design and optimize state-of-the art experimental protocols for gene modulation and cell line/primary cell engineering, including RNA interference, stable transfection and CRISPR-Cas9 mediated gene editing, in order to study signalling pathways of interest.
• Independently analyse experimental results, and present data analysis and plans at cross-functional meetings.

Education

• MSc with 1+ years of experience or Ph D in Immunology, Molecular Biology or Cellular Biology

Specific Knowledge

• Experience in cell culture. Experience with primary immune cells (PBMC, lymphocytes…) or with skin cells such as primary keratinocytes.
• Theoretical and experimental background in cellular assays such as flow cytometry, ELISA, HTRF, q PCR, WB. Experience with functional immunology assays (e.g. PBMC activation, MLRs) and spectral flow cytometry would be a plus.
• Experience with gene modulation assays (si RNA and plasmids transfection, lentiviral transduction of sh RNA…) would be a plus.
• Interest in new therapeutic modalities such as bispecific antibodies, Targeted Protein Degradation, cell or m RNA therapies would be a plus.
• Excellent organization skills and track record for generation of high data quality.
• Track record of continual growth, curiosity, and drive to learn.
• Team player with ability to collaborate and communicate effectively across several scientific disciplines.
• Advanced English level required.

Values

• Care: we listen & empathize, we value diverse perspectives & backgrounds and we help each other succeed.
• Courage: we challenge the status quo, we take full ownership and we learn from our success & failures
• Innovation: we put the patient and customer at the center, we create novel solutions and we empower entrepreneurial mindsets.
• Simplicity: we act decisively and avoid over-analysis, we understand why before we act and we are agile & keep things simple.