Denmark Job Openings

Novo Nordisk

Associate Scientist, Stem cell development for target and drug discovery

Måløv

August 19, 2024

Associate Scientist, Stem cell development for target and drug discovery
Category: Research
Location:Måløv, Capital Region of Denmark, DK
Are you passionate about developing cellular models that are poised to improve the predictive validity and translatability of new drug targets? Are you excited to contribute to the early operations and science of a new research team? Do you have a stem cell differentiation background and an eagerness for fast-paced, hands-on laboratory work? Importantly, do you believe in a culture of collaboration, curiosity, and innovation?

If yes, then you might be the one we are looking for to contribute to the GEM CELL Hub (Genome Engineering & Manufacturing of Stem Cell-Derived Cell Types), a new project to generate stem cell-derived cell types for target discovery, screening assay development, and drug screening. Apply today and become part of Novo Nordisk's mission to improve lives through innovative pharmaceutical solutions.

The position
As the Associate Scientist, you will be based in Måløv, Denmark and work closely with a Principal Scientist. Your primary responsibility will be the establishment of processes for h PSC culture and the scalable production of h PSC-derived cell types with high reproducibility and functionality. This will involve close interactions with the Principal Scientist and a growing team of scientists and technicians.

Bringing together competences within stem cell biology, molecular biology, assay technology, analytics, cell physiology, and cultivation technology, the Associate Scientist will play a key role in enabling accelerated target discovery and drug screening in early-stage research.

The main responsibilities can be summarized as follows:
  • Together with a Principal Scientist, establish laboratory infrastructure and workflows for stem cell cultivation, differentiation and characterization, focusing on robustness, functionality and scalability.
  • Design and execute experiments to optimize differentiation protocols, utilizing cutting-edge bioprocessing techniques for 2D and 3D culture.
  • Employ molecular biology techniques to characterize and quality control stem cells and their cellular derivatives.
  • Collaborate with cross-functional teams to translate established stem cell differentiation protocols into large-scale manufacturing processes.
  • Analyze and interpret experimental data.

Qualifications
To thrive and succeed in the role, you should have:
  • A MSc degree in Cell Biology, Chemistry, Chemical Engineering, Biochemistry or a related field.
  • Hands-on experience in stem cell propagation and differentiation process development, and knowledge of gene editing and cultivation strategies for stem cells. It will be an advantage if you have experience from the pharmaceutical or biotechnology industries.
  • Knowledge of high-throughput screening techniques to inform and develop assays for drug discovery.
  • Familiarity with automated liquid handling systems and robotics.
  • Hands-on experience with establishment of bioreactor-based processes.

Your role will require a highly structured, organized and operational mindset, and a working style that balances both, innovative ideas and the focus on key deliverables. Moreover, you are a team player who displays excellent collaboration and communication skills across all organizational levels, functions, and cultures. You also thrive working in a fast-paced and dynamic environment.

About the project
The GEM CELL Hub will be based in Bioprocess Research, Global Research Technologies, representing a new effort to bolster our drug discovery program using stem cell-derived cell types for target discovery and drug screening and related purposes. The primary aim is to ensure the accessibility of top-tier stem cell-derived cells for the diverse applications, catering to varying demands for cell types, quality, quantities and thereby also requiring the need for ongoing research and development of methods and processes. Ultimately, the goal is to facilitate the distribution of cells to stakeholders across the globe. The project will benefit from synergies of being co-localized with our cultivation experts in the area while having easy access to assay development colleagues and experts from our therapeutic stem cell area.

Working at Novo Nordisk
At Novo Nordisk, we do not wait for change. We drive it. We are a dynamic company in an even more dynamic industry, and we know that what got us to where we are today is not necessarily what will make us successful in the future. We embrace the spirit of experimentation, striving for excellence, without fixating on perfection. We never shy away from opportunities to develop, we seize them. From research and development to manufacturing, marketing, and sales – we’re all working to move the needle on patient care.

Contact
For further information, please contact Charis Segeritz-Walko, Director for GEM CELL Hub, at +45 30798169.

Deadline
1 September 2024.

Applications will be reviewed on an ongoing basis, so we encourage you to apply as soon as possible.

You do not need to attach a cover letter to your application, but please include a few sentences about why you are applying in your resume or CV. To ensure an efficient and fair recruitment process, please refrain from adding a photo to your CV.
We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.
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