Norway Job Openings
Oslo universitetssykehus
Laboratory engineer for organoid research
Oslo
FULL TIME
November 19, 2024
The Centre headed by Prof. Stefan Krauss is located at the Institute of Basic Medical Sciences at University of Oslo, with partners at the University of Glasgow and Imperial College, London. The overall objective of the Centre is to develop innovative human 3D models (3D organoids and organ-on-chip systems) for experimental drug testing and animal testing replacement (https://www.med.uio.no/hth/english/).
The laboratory engineer will participate in the development of advanced in vitro liver organoids for disease modelling and drug testing. The work will include culture and differentiation of human embryonic and induced pluripotent stem cells, culture of 3D organoids, and culture of 3D organoids in a microfluidic platform under various conditions including drug testing. The laboratory engineer will also assist with RNA/DNA isolation, RNA-seq library preparation and ELISA.
Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!
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Human stem cell culture and differentiation, including organoid/spheroid formation, culture of cells and organoids/spheroids in a microfluidic system.
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Assays, including drug testing, on organoids/spheroids.
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Molecular biology experiments including DNA/RNA isolation, q PCR, RNA-seq library preparation.
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Biochemical assays and ELISA, confocal and fluorescent microscopy.
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Contributing to the day-to-day running of the lab, including ordering system and cleaning routines.
- Maintaining excellent laboratory notebooks (manual and/or electronic) to document all aspects of the experimental work.
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A Bachelor’s or Master’s degree in molecular biology, biochemistry, genetics, biotechnology or a similar subject is required.
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Minimum of half-year laboratory experience is required.
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Experience with basic molecular biology is required.
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Experience with immunofluorescent microscopy methods is required.
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Experience with human cell culture is required.
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Experience with primary cell cultures and liver models is an advantage.
- Experience with human pluripotent stem cell culture, differentiation protocols and organoids is an advantage Good knowledge in cell biology, developmental biology and histology is an advantage.
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Independent work and troubleshooting.
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Ability to learn quickly and work in a fast-paced multidisciplinary environment.
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Team player.
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Fluent in spoken and written English.
- Flexibility of working on weekends (2-3 hours).
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A positive and stimulating international working environment with experienced staff.
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Salary according to agreement.
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Competetive conditions.
- Flexible working hours. Possibility of extension.
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