Responsibilities

• Manage, plan and execute in-vitro radiobiology studies to enable development of ARTBIO novel radioligand candidates from early Discovery to IND-readiness according to the company’s strategy.
• Design and execution of radiolabelling and analytical characterisation of radioligands and assessment of quality in close collaboration with the in-vitro radiochemistry team.
• Interface with project team and leadership to lead project goals and experimental design for drug development.
• Collaborate with external vendors and academic facilities for sourcing of reagents and execution of experimental activities.
• Provide mentorship and supervision to other ARTBIO preclinical team members so that experiments and projects are performed according to plan and internal ways of working.
• Support writing of regulatory documentation related to pre-clinical studies for RLT candidates selected for clinical development.
• Provide deep scientific expertise to guide selection of novel targets, candidate molecules and best experimental approaches to address relevant, scientific questions.
• Develop innovative solutions to mitigate research challenges & increase throughput and processes efficiency.
• Oversee data collection, analysis, interpretation, reporting and presentation.
• Multi-task and collaborate effectively with other scientists and research associates to accomplish goals on tight timelines. Ability to navigate in a start-up environment and adapt in the ‘unknown’
• Maintain compliance with lab documentation to enable collaboration among multinational project teams
• Analyse experimental results, brainstorm and troubleshoot findings thoughtfully and proactively
• Work seamlessly in matrixed environment to ensure technical support across programs

Qualifications & Education

• Phd or equivalent degree in Molecular Biology, Radioligand therapy development, Radiation Biology, or other relevant discipline with a significant laboratory-based skills component.
• At least 5 years working in research projects, particularly in drug discovery and in vitro testing of novel radioligands.
• Preferred industry experience, preferably radioligand therapy or oncology.
• Good English speaking and writing skills.
• Critical understanding of the principles of receptor pharmacology theory and experimental methodologies to assess ligand binding.
• Specific experience with radioligand therapy development, including radiolabelling and radiopharmaceutical applications.
• Proficiency in radiation safety practices and regulations, including working with open sources and radionuclides.
• Proven ability to develop, optimize, and validate novel in-vitro methods and techniques and creating and implementing high throughput screening methods to streamline research processes.
• Experience with Analytical Techniques such as use of gamma counters, Germanium Detectors, Dose calibrators, Thin Layer Chromatography and High-Performance Liquid Chromatography is a plus.
• Conducting and interpreting internalization assays to understand cellular uptake of radioligands.
• Strong analytical skills for processing and interpreting complex experimental data.
• Ability to work effectively within interdisciplinary teams and contribute to collaborative research efforts.
• Excellent communication skills for writing reports, preparing presentations, and publishing research findings.
• Experience managing research projects, timelines, and resources.
• Line management experience, including supervising and mentoring junior scientists.
• Demonstrated problem-solving abilities and innovation in addressing research challenges.
• Focus on the “we” rather than the “me”
• Motivated by patients, passionate about our company culture, inclusive and respectful of all colleagues