• Testing the role and therapeutic potential of small noncoding RNAs and epigenetic mechanisms using small molecule, antisense oligonucleotide and gene therapy-based treatments for acquired and genetic forms of epilepsy, including, but not limited to:
• Perform steterotaxic surgery in rodents such as mice to induce and record seizures
• Deliver and evaluate the effects of experimental therapeutics such as small molecules, antisense oligonucleotides and gene therapies
• Perform behavioral and other assessments of therapeutic effects in rodent models
• Assist with husbandry and colony maintenance
• Perform biochemical, pharmacological and molecular analyses of the role of the identified RNAs and pathways in appropriate animal model of CDD, including analysis of gene expression, brain function and histopathology

• Liaise with industry partners and colleagues funded by relevant agencies for purposes of collating, interpreting, reporting findings
• Generate, support and submit funding applications and funding agency reports
• Develop and submit funding applications
• Compliance with animal and human ethics requirements
• Biobanking/curating tissue and biofluid resources relating to the project
• Generate original peer-reviewed publications
• Identify opportunities for IP

• Organising and drafting reports for internal and external stakeholders
• Providing support in the monitoring of progress of research activities of the group
• Supporting and participating in the Centre’s research activities
• Complying with statutory legislation, RCSI and department rules and requirements in furtherance of your own and general staff welfare and safety
• Undergoing programmes of training and development as may be required from time to time
• Representing the best interests of the department and RCSI at all times
• Performing such other duties as may be required from time to time

• A Ph D in neuroscience, pharmacology or related discipline
• Research in the field of Neuroscience or closely-related brain disease
• Careful and organized and able to interact in a busy scientific and, in some cases, clinical environment
• Experience and a proven track record in a similar role is desirable
• Effective communications style
• Proficiency in Computer/Presentation skills
• Ability to make decisions and meet deadlines
• Ability to work on one’s own initiative as well as in a team environment

• Onsite gym €10 per month
• Flexible working arrangements
• Automatic enrolment to a pension scheme for all employees (Willis Towers Watson, pension documents outlined below)
• RCSI Investment Guide
• Pension Scheme Guide
• Benefit Schedule
• Life assurance/death in service
• Long term illness/disability income replacement
• Free advice on health/motor and home insurance
• Discounted services, including GP
• Support for parents and carers
• Taxsaver commuter tickets
• Biketo Work
• Free eye test at the National Optometry centre
• €12/day for parking for all RSCI staff in the St. Stephens green/RCSI car park
• RCSI’s Learning and Development team facilitate and provide training opportunities for all staff
• Sports and social club
• Opportunities to volunteer in the community
• 26.5 days leave - 20 days annual leave plus 6.5 days Privilege days - In addition to your annual leave entitlements and public holidays, RCSI also grants privilege days to our employees (paid time off during Easter and Christmas periods). We also offer a number of leave options to support the working lives of our employees.
• Paid maternity leave
• Paid Paternity leave
• Parental leave